Investigating phase separation mechanisms for transcriptional control submitted by Marc Böhning ; 1st Reviewer: Prof. Dr. Patrick Cramer, 2nd Reviewer: Prof. Dr. Henning Urlaub, Further members of the Examination Board: Prfo. Dr. Markus Zweckstetter, Prof. Dr. Argyris Papantonis, Prof. Dr. Herbert Jäckle, Dr. Peter Lenart 

Erscheinungsform: einbändiges Werk
Autor/Urheber:
  • Böhning, Marc
Beteiligte:
  • Cramer, Patrick
  • Urlaub, Henning
  • Zweckstetter, Markus H.-G. S.
  • Papantōnēs, Akēs
  • Jäckle, Herbert
  • Lénárt, Péter
Umfang: 1 Online-Ressource Illustrationen, Diagramme
Identifikatoren/​Sonstige Nummern: 173871411X [PPN]
Inhalt:
  • Transcription of protein-coding genes by RNA polymerase (Pol) II is a highly coordinated process. In metazoan cells, transcription is regulated both at the initiation step by recruitment of the Pol II machinery as well as during early elongation by promoter-proximal pausing. Prior to transcription initiation, Pol II forms short-lived clusters near active gene promoters, but the underlying molecular basis has remained unknown. Pol II possesses a disordered C-terminal heptad repeat domain (CTD) that is essential for factor recruitment during the transcription cycle. CTD length is organism-spe...
URL: http://hdl.handle.net/21.11130/00-1735-0000-0005-14EC-B
Weiter im Partnersystem: https://swb.bsz-bw.de/DB=2.1/PPNSET?PPN=173871411X
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