Regulation of binding of HP1 associated complexes to chromatin and their role in transcription regulation in C. elegans vulva development vorgelegt von Yogesh Ostwal 

Erscheinungsform: einbändiges Werk
Autor/Urheber:
  • Ostwal, Yogesh
Beteiligte:
Umfang: 1 Online-Ressource Illustrationen
Identifikatoren/​Sonstige Nummern: 87130578X [PPN]
Inhalt:
  • HP1 proteins are known to bind to H3K9me3 and thereby localize to heterochromatin. However, direct functions of HP1 in heterochromatin formation and maintenance are not clear. This is partially due to essentiality of HP1 proteins in mammals and flies. We therefore, explored the functions of HP-1 homologues in C. elegans. Our findings suggest that the C. elegans HP1 homologue; HPL-2 does not directly bind H3K9me3, unlike what has been proposed for HP1 family proteins. Interestingly, HPL-2 depends on LIN-61 for association with H3K9me3. Our analysis of LIN-61-H3K9me3 interaction defective mut...
URL: http://hdl.handle.net/11858/00-1735-0000-002B-7C4F-6
Weiter im Partnersystem: https://swb.bsz-bw.de/DB=2.1/PPNSET?PPN=87130578X
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