Investigating phase separation mechanisms for transcriptional control submitted by Marc Böhning ; 1st Reviewer: Prof. Dr. Patrick Cramer, 2nd Reviewer: Prof. Dr. Henning Urlaub, Further members of the Examination Board: Prfo. Dr. Markus Zweckstetter, Prof. Dr. Argyris Papantonis, Prof. Dr. Herbert Jäckle, Dr. Peter Lenart
Erscheinungsform: | einbändiges Werk |
Autor/Urheber: | |
Beteiligte: | - Cramer, Patrick
- Urlaub, Henning
- Zweckstetter, Markus H.-G. S.
- Papantōnēs, Akēs
- Jäckle, Herbert
- Lénárt, Péter
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Umfang: | 1 Online-Ressource Illustrationen, Diagramme |
Identifikatoren/Sonstige Nummern: | 173871411X [PPN] |
Inhalt: | - Transcription of protein-coding genes by RNA polymerase (Pol) II is a highly coordinated process. In metazoan cells, transcription is regulated both at the initiation step by recruitment of the Pol II machinery as well as during early elongation by promoter-proximal pausing. Prior to transcription initiation, Pol II forms short-lived clusters near active gene promoters, but the underlying molecular basis has remained unknown. Pol II possesses a disordered C-terminal heptad repeat domain (CTD) that is essential for factor recruitment during the transcription cycle. CTD length is organism-spe...
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URL: | http://hdl.handle.net/21.11130/00-1735-0000-0005-14EC-B |
Weiter im Partnersystem: | https://swb.bsz-bw.de/DB=2.1/PPNSET?PPN=173871411X |